rs33980500
|
|
|
0.850 |
GeneticVariation |
BEFREE |
We have replicated the association of TRAF3IP2-_rs33980500 variant with the susceptibility to psoriasis.
|
24005976 |
2014 |
rs33980500
|
|
|
0.850 |
GeneticVariation |
BEFREE |
The hyperactive Th17 response combined with fully responsive fibroblasts likely synergized to contribute to psoriasis susceptibility in SNP-D10N patients.
|
25024377 |
2014 |
rs13196377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Minor allele of this SNP was always present in two haplotypes found to be associated with increased psoriasis risk: rs13196377_G + rs13190932_G + rs33980500_T + rs13210247_A (OR = 2.7, p = 0.0054) and rs13196377_A + rs13190932_A + rs33980500_T + rs13210247_G (OR = 1.8, p = 0.0008).
|
24005976 |
2014 |
rs33980500
|
|
|
0.850 |
GeneticVariation |
BEFREE |
In the absence of IL-17 signaling, IL-22 was the main contributor to skin inflammation, which provides a molecular mechanism for the association of Act1(D10N) with psoriasis susceptibility.
|
23202271 |
2013 |
rs33980500
|
|
T |
0.850 |
GeneticVariation |
GWASCAT |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
|
23143594 |
2012 |
rs33980500
|
|
|
0.850 |
GeneticVariation |
GWASDB |
Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity.
|
23143594 |
2012 |
rs7769061
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.
|
25903422 |
2015 |
rs33980500
|
|
T |
0.850 |
GeneticVariation |
GWASCAT |
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
|
20953188 |
2010 |
rs33980500
|
|
T |
0.850 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
|
20953188 |
2010 |
rs13210247
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
|
20953188 |
2010 |
rs33980500
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Collectively, these results implicate NETs and the Act1 D10N variant in human Th17 induction from peripheral blood mononuclear cells, with ramifications for immunogenetic studies of psoriasis and other autoimmune diseases.
|
30528823 |
2019 |
rs33980500
|
|
|
0.850 |
GeneticVariation |
BEFREE |
Collectively, these results implicate NETs and the Act1 D</span>10N variant in human Th17 induction from peripheral blood mononuclear cells, with ramifications for immunogenetic studies of psoriasis and other autoimmune diseases.
|
30528823 |
2019 |
rs33980500
|
|
|
0.850 |
GeneticVariation |
BEFREE |
By contrast, healthy individuals homozygous for the common variant D10N, located in the ACT1 tumor necrosis factor receptor-associated factor-interacting domain and previously associated with psoriasis, had impaired, but not abolished, responses to IL-17 cytokines.
|
24120361 |
2013 |